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OECD 442C: Direct peptide reactivity assay (DPRA) for skin sensitization

OECD 442C: Direct peptide reactivity assay (DPRA) for skin sensitization

The Direct Peptide Reactivity Assay (DPRA) is effectively used to test the sensitivity potential of a chemical as a human health hazard on the skin. 

The test, adopted by the OECD and the EU, measures the reactivity of a test compound with model synthetic peptides containing either lysine or cysteine. The assay is used to test between skin sensitizers and non-sensitizers.

Industry Market

Crop, Chemical, Pharma

Phase

Nonclinical