Online Catalog

Search for common nonclinical studies and assays; customization is possible.

Toxicity studies: Acute

Toxicity studies: Acute

Acute Toxicity Studies evaluate short-term serious adverse effects after clinical and parenteral administration either as a single dose or in multiple doses during 24 hours. 

The test uses two mammalian species, including one non-rodent, and provides the following information:

  • Potential for acute toxicity in humans 
  • Potential for toxicity against the target organs
  • The time course of drug-induced effects
  • An appropriate dosage for multiple-dose toxicity studies
  • Species differences in toxicity

Data on acute toxicity can predict the outcome in human overdose and supports Phase III clinical trials.

Molecule or Product Type

Small Molecule, Biologics

Administration Routes

Dermal, Intravenous, Dietary

Industry Market

Pharma, Device